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Bronchoalveolar Lavage Fluid Cytology in Culture-Documented Invasive Pulmonary Aspergillosis in Patients with Hematologic Diseases: Analysis of 67 Episodes

Year: 2018
Type: article
Study design: Observational Study
Abstract: There is a paucity of studies on the yield of Gomori-methenamine-silver (GMS) staining in bronchoalveolar lavage (BAL) fluid cytology and its comparison with fluorescent dye staining for the diagnosis of invasive pulmonary aspergillosis (IPA) in patients with hematologic malignancies. To that end, we analyzed the yield of direct fungal visualization in BAL fluid cytology with GMS staining, in a series of culture-positive IPA cases in 67 patients with hematologic malignancies, and we compared the results with those of direct examination with calcofluor white staining and BAL fluid galactomannan assays, when available.
DOI: 10.1128/jcm.00962-18
Authors: A. Fernández-Cruz, E. Magira, S. T. Heo, S. Evans, J. Tarrand, D. P. Kontoyiannis
Institutions: The University of Texas MD Anderson Cancer Center, Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, National and Kapodistrian University of Athens, Evangelismos Hospital, Jeju National University Hospital, Jeju National University
Language: English
Field: Medicine
Open Access status: green
OpenAlex ID: W2883998301
FWCI: 1.401
Cites: 13
Cited by: 18
Related to: 10