Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration
Work
Year: 2018
Type: article
Abstract: Alzheimer's disease (AD) is characterized by accumulation of β-amyloid plaques (AP) and neurofibrillary tangles (NFT) in the cortex, together with synaptic loss and amyloid angiopathy. Perturbations i... more
Source: Brain Pathology
Institutions National University of Singapore, National University Health System, King's College London, Newcastle Hospitals - Campus for Ageing and Vitality, Newcastle University +1 more
Cites: 74
Cited by: 59
Related to: 10
FWCI: 4.002
Citation percentile (by year/subfield): 88.74
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
Sustainable Development Goal Good health and well-being
Open Access status: bronze
Grant IDS G0400074, NMRC/CSA‐SI/007/2016