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Early Liver Transplantation is a Viable Treatment Option in Severe Acute Alcoholic Hepatitis

Year: 2018

Type: article

Study design: Observational Study

Abstract: Liver transplantation is lifesaving for patients with severe acute alcoholic hepatitis (SAH) with preliminary data demonstrating favorable early post-transplant outcomes. Using the United Network for Organ Sharing database, we demonstrate that liver transplantation for SAH in the USA has steadily increased and is associated with similar 1- and 3-year post-transplant survival as well as comparable 30-day waitlist mortality to acute liver failure due to drug-induced liver injury.

Source: Alcohol and Alcoholism

DOI: 10.1093/alcalc/agy056

Authors: Puneet Puri, George Cholankeril, Thomas Y Myint, Aparna Goel, Shiv Kumar Sarin, Ann M Harper, Aijaz Ahmed

Institutions: Hunter Holmes McGuire VA Medical Center, Virginia Commonwealth University Medical Center, Stanford Medicine, Stanford University, Santa Clara Valley Medical Center, Institute of Liver and Biliary Sciences, United Network for Organ Sharing

Language: English

Topic: Liver Disease and Transplantation

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: U.S. Department of Health and Human Services, National Institutes of Health, Health Resources and Services Administration, National Institute on Alcohol Abuse and Alcoholism

Awards: G232100374, G2615208926, G3533336020, G369916386, G8919324196, G9000152540, G9000201515

OpenAlex ID: W2885576262

FWCI: 1.735

Cites: 7

Cited by: 15

Related to: 10