Work

Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing

Year: 2018

Type: article

Source: Journal of Investigative Dermatology

DOI: 10.1016/j.jid.2018.07.016

Authors: Gabriele Fenini, Serena Grossi, Emmanuel Contassot, Thomas Biedermann, Ernst Reichmann, Lars E. French, Hans-Dietmar Beer

Institutions: University Hospital Zurich, University of Zurich, University Children's Hospital Zurich

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Wilhelm Sander-Stiftung, OPO-Stiftung, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Promedica Stiftung, Julius Müller Stiftung, Kurt und Senta Herrmann Stiftung

Awards: Investigation of the molecular mechanisms of NLRP3 inflammasome activation and its relevance in inflammatory skin disease, Role of the IL-1beta-processing inflammasome in the pathogenesis os severe skin disease

OpenAlex ID: W2886580824

FWCI: 3.412

Cites: 51

Cited by: 121

Related to: 10