Work

It's Not All in the Conditioning or the Perils of Early Trial Cessation

Year: 2018

Type: article

Abstract: Reduced-intensity conditioning (RIC) regimens were initially developed in an effort to offer a potential curative treatment to patients who were historically not considered candidates for allogeneic transplantation either because of age or advanced comorbidities. The lower treatment-related mortality (TRM) of these regimens led to an interest in exploring RIC in healthier and younger patients. Many retrospective studies showed no difference in overall survival (OS) compared with higher intensity conditioning regimens referred to as myeloablative conditioning (MAC) [1-3].

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2018.08.014

Author: Bart L. Scott

Institutions: University of Washington, Fred Hutch Cancer Center

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650