Reactive Oxygen Species (ROS) in Living Cells
Year: 2018
Type: book
Abstract: Oxygen represents only 20% of the Earth's atmosphere, yet it is vital for the survival of aerobic organisms. There is a dark part of the use of oxygen that consists in generating reactive species that are potentially harmful to living organisms. Moreover, reactive oxygen species can combine with nitrogen derivatives and generate many other reactive species. Thus, living organisms are continuously assaulted by reactive species from external or internal sources. However, the real danger comes in the case of high concentrations and prolonged exposure to these species. This book presents an image of the mechanisms of action of reactive species and emphasizes their involvement in diseases. Inflammation and cancer are examined to determine when and how reactive species turn the evolution of a benign process to a malignant one. Some answers may come from recent studies indicating that reactive species are responsible for epigenetic changes.
Source: InTech eBooks
Authors: Cristiana Filip, Elena Albu
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
Funders: Alexander von Humboldt-Stiftung, Chulalongkorn University, Government of Jiangsu Province, Thailand Research Fund, National Research Council of Thailand, Novartis Pharma, Japan Society for the Promotion of Science, Japan Science and Technology Agency, Faculty of Medicine, Chulalongkorn University, Science and Technology Research Partnership for Sustainable Development
OpenAlex ID: W2887203428