Work

Continuous directed evolution of proteins with improved soluble expression

Year: 2018

Type: article

Source: Nature Chemical Biology

DOI: 10.1038/s41589-018-0121-5

Authors: Tina Wang, Ahmed H. Badran, Tony P. Huang, David R. Liu

Institutions: Broad Institute, Harvard University, Howard Hughes Medical Institute

Language: English

Topic: Evolution and Genetic Dynamics

Subfield: Genetics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Human Genome Research Institute, National Institute of General Medical Sciences, National Institute of Biomedical Imaging and Bioengineering

Awards: Continuous Evolution of Proteins with Novel Therapeutic Potential, Engineering Protein Stability Through Phage-Assisted Continuous Evolution, Integrating Chemistry and Evolution to Illuminate Biology and Enable Novel Therapeutics, Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease

OpenAlex ID: W2887744121

FWCI: 7.051

Cites: 49

Cited by: 106

Related to: 10