Work

Identification of 4-isopropyl–thiotropolone as a novel anti-microbial: regioselective synthesis, NMR characterization, and biological evaluation

Year: 2018

Type: article

Abstract: 4-Isopropyl–thiotropolone was identified as a novel anti-microbial agent with good therapeutic index and ADME properties.

Source: RSC Advances

DOI: 10.1039/c8ra06297h

Authors: Mohamed Elagawany, Lamees Hegazy, Feng Cao, Maureen J. Donlin, Nigam Rath, John Tavis, Bahaa Elgendy

Institutions: Damanhour University, Saint Louis University, United States Department of Veterans Affairs, Veterans Health Administration, St. Louis VA Medical Center, John Cochran VA Medical Center, University of Missouri–St. Louis, Benha University

Language: English

Topic: Synthesis and biological activity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funders: National Science Foundation, Saint Louis University, Division of Chemistry

Award: Upgrade of a CCD-based X-Ray Diffraction Laboratory

OpenAlex ID: W2888065228

FWCI: 0.49

Cites: 39

Cited by: 16

Related to: 10