Human Rad52 Promotes XPG-Mediated R-loop Processing to Initiate Transcription-Associated Homologous Recombination Repair
Year: 2018
Type: article
Source: Cell
Institutions: Center for Disease Biology and Integrative Medicine, The University of Tokyo, The University of Tokyo, Gunma University, National Cancer Center Research Institute, Nagasaki University, Atomic Bomb Disease Institute, Nagasaki University, Institute for Advanced Co-Creation Studies, The University of Osaka, The University of Osaka
Language: English
Topic: DNA Repair Mechanisms
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
Awards: ATR functional analysis using in vitro DNA replication system, Regulation of DNA repair pathway choice and gene editing by DNA repair machinery, The roles of R-loop structure in DNA damage signaling and genome, Analysis of pseudo transcription formation following transcription remodeling leading to homologous recombination repair, Elucidation of the mechanism underlying tumor initiation via DNA replication stress regulated by ATR, Regulation of asymmetric cell division by the machinery maintaining genome stability, Elucidation of the mechanism underlying DNA replication stress response regulating genomic instability, Regulation of radiation sensitivity by a pathway linking DNA repair with cell-cycle control, Elucidation of the mechanism leading to the initiation of transcription associated homologous recombination, Mechanism for cancer-related upregulation of the Rad54B-mediated cellular function network
OpenAlex ID: W2889676858