Work

Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design

Year: 2018

Type: article

Source: Nature Chemistry

DOI: 10.1038/s41557-018-0147-z

Authors: Qin Cao, Woo Shik Shin, Henry Chan, Celine K. Vuong, Bethany Dubois, Binsen Li, Kevin A. Murray, Michael R. Sawaya, Juli Feigon, Douglas L. Black, David S. Eisenberg, Lin Jiang

Institutions: Howard Hughes Medical Institute, University of California, Los Angeles, Salk Institute for Biological Studies, Brown University

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Office of Science, National Institute on Aging, National Institute of General Medical Sciences, National Center for Research Resources, Argonne National Laboratory

Awards: Pixel Array Detector for X-ray Crystallography, Mechanisms of Alternative Splicing Regulation by Rbfox Proteins, Structure and Inhibition of Amyloid in Alzheimer's Disease, NE-CAT Center for Advanced Macromolecular Crystallography

OpenAlex ID: W2889706274

FWCI: 4.628

Cites: 47

Cited by: 75

Related to: 10