Get started
Work

Antiretroviral Concentrations in Hair Strongly Predict Virologic Response in a Large Human Immunodeficiency Virus Treatment-naive Clinical Trial

Year: 2018
Type: article
Abstract: Concentrations of antiretrovirals in hair are associated with virologic outcomes in cohorts of human immunodeficiency virus (HIV)-positive individuals but have never been examined in a clinical trial. We show for the first time the predictive utility of hair antiretroviral concentrations in a large HIV treatment-naive trial (AIDS Clinical Trials Group protocol A5257).
DOI: 10.1093/cid/ciy764
Authors: Monica Gandhi, Peter Bacchetti, Igho Ofokotun, Chengshi Jin, Heather J Ribaudo, David W Haas, Anandi N Sheth, Howard Horng, Nhi Phung, Karen Kuncze, Hideaki Okochi, Raphael J Landovitz, Jeffrey Lennox, Judith S Currier
Institutions: University of California, San Francisco, Emory University, Harvard University, Meharry Medical College, Vanderbilt University, University of California, Los Angeles
Language: English
Field: Medicine
Open Access status: bronze
Funders: Gilead Sciences, AIDS Clinical Trials Group, National Institutes of Health, University of California, San Francisco, National Institute of Allergy and Infectious Diseases, National Center for Advancing Translational Sciences
Awards: G1050281965, G1276011396, G1819583291, G2127051194, G2244966566, G243619197, G2548217053, G285461174, G3122377644, G3347964049, G3441327761, G3590247099, G3726674119, G374818150, G3810609436, G3936936596, G4042995567, G4099673573, G4553935269, G4697592129, G6488665543, G762740169, G857487509, G8614342735, Clinical and Translational Science Collaborative of Cleveland, G9000039438, G9000047228, G9000053760, G9000054231, Tennessee Center for AIDS Research (TN-CFAR), G9000103943, G9000107657, G9000112699, G9000126704, G9000182931, G9000195116, G9000263428, G9000292181, G9000313355, AIDS Clinical Trial Group Laboratory Center, NRSA Training Core, The University of North Carolina Center for AIDS Research, G95160140, G97119092
OpenAlex ID: W2889877489
FWCI: 2.766
Cites: 13
Cited by: 23
Related to: 10