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A phase 1b dose-escalation study of prexasertib, a checkpoint kinase 1 (CHK1) inhibitor, in combination with cisplatin in patients with advanced cancer.

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Year: 2018
Type: conference-abstract
Source: Journal of Clinical Oncology
DOI: 10.1200/jco.2018.36.15_suppl.2579
Authors: Manish R. Patel, David S. Hong, Johanna C. Bendell, Suzanne Fields Jones, Erika Paige Hamilton, Vivek Subbiah, Daniel D. Karp, Judy Sing-Zan Wang, Raid Aljumaily, Scott Hynes, Rod Decker, Michele Niland, Xuejing Aimee Wang, Aimee K. Lin, Kathleen N. Moore
Institutions: The University of Texas MD Anderson Cancer Center, Sarah Cannon, Tennessee Oncology, Johns Hopkins Medicine, University of Oklahoma Medical Center, Eli Lilly (United States), University of Oklahoma Health Sciences Center
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W2890083017
Cites:
Cited by: 5
Related to: 10
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