Year: 2018
Type: article
Abstract: T-cell large granular lymphocytic leukemia and plasma cell disordersAlthough neutropenia is not common as an initial presentation in patients with multiple myeloma (MM), it is a common adverse effect of the therapy used for MM and a more frequent problem in relapsed or refractory disease. 1-3In rare cases, neutropenia may accompany the diagnosis of monoclonal gammopathy of undetermined significance (MGUS). 4T-cell large granular lymphocytic (T-LGL) leukemia is a chronic lymphoproliferative disorder characterized by a clonal expansion of T-LGLs with a cytotoxic phenotype (CD3, CD8, and CD57). 5It is a relatively rare malignancy and accounts for 2-5% of chronic lymphoproliferative diseases in the US. 6 T-LGL leukemia
Source: Haematologica
Institution: Mayo Clinic
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,157
OpenAlex ID: W2890373146