Year: 2018
Type: review
Abstract: Intravital microscopic imaging can uncover fundamental aspects of immune cell behavior in real time in both healthy and pathological states. Here, we discuss approaches for single-cell imaging of adaptive and innate immune cells to explore how they migrate, communicate, and mediate regulatory or effector functions in various tissues throughout the body. We further review how intravital single-cell imaging can be used to study drug effects on immune cells.
Source: Science Immunology
Language: English
Subfield: Biophysics
Domain: Life Sciences
Open Access status: bronze
Awards: Single Cell Genome-Wide Myeloid Response Profiling in Immunotherapy, Imaging tumor associated macrophage (TAM) function, Analysis of scant cancer cells in fine needle aspirates, In vivo behavior of monocytes in resting and inflammatory conditions, G531883626, The Role of Driver Mutations in Lung Cancer Response to Anti-PD-1 Therapy, Imaging of nanotherapeutic drug action, G9000276416, Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital, Cellular mechanisms by which exhausted T cell responses are restored, TRAINING GRANT IN MOLECUCLAR IMAGING RESEARCH AND CANCER SYSTEMS ANALYSIS
OpenAlex ID: W2890684496