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Differential diagnosis of MELAS syndrome from viral encephalitis by MRI: A case report

Year: 2018
Type: article
Study design: Case Report
Abstract: Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) syndrome and viral encephalitis have little difference and the diagnosis is often uncertain based on clinical manifestations, even biochemical immune indicators couldn't make a definitive diagnosis. However, magnetic resonance imaging (MRI) seems to be able to provide a more definitive diagnosis. A sick boy with headache, vomiting and convulsions, and 12 h unconsciousness was admitted to Kunming Children's hospital. After physical examination and history collection, blood and cerebrospinal fluid (CSF) were taken for laboratory tests, including cell count, blood gas analysis. Computer tomography (CT) and magnetic resonance imaging (MRI) of the brain were performed. MRI was first performed on October 7, 2017. All these finding suggested the diagnosis of viral encephalitis. A repeat MRI was performed on October 23, 2017, which showed resolution of lesions at the bilateral frontal and temporal lobe regions, but emerging new bilateral putaminal lesions, compared with previous MRI examination. MRI examination could be a useful tool in the diagnosis of MELAS syndrome.
Authors: Lin Zhang, Jun Zhou
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W2890712428
FWCI:
Cites: 4
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Related to: 10