Work

ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P

Year: 2018

Type: article

Source: Cell

DOI: 10.1016/j.cell.2018.08.020

Authors: Ju Youn Kim, Ricard Garcia-Carbonell, Shinichiro Yamachika, Peng Zhao, Debanjan Dhar, Rohit Loomba, Randal J. Kaufman, Alan R. Saltiel, Michael Karin

Institutions: University of California San Diego, Sanford Burnham Prebys Medical Discovery Institute

Language: English

Topic: Liver Disease Diagnosis and Treatment

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Childhood Cancer Foundation, CureSearch for Children's Cancer, Johns Hopkins University, Boehringer Ingelheim Fonds, National Institutes of Health, National Health and Medical Research Council, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Environmental Health Sciences

Awards: DETECTION AND MODELS OF TOXICANT EXPOSURE, G4562190268, The Role of the Exocyst Complex in Insulin Regulated Glucose Transport, ER stress and UPR in non-alcoholic steatohepatitis and hepatocellular carcinoma, TOR signaling and autophagy in obesity-promoted liver tumorigenesis, Role of p62/SQSTM1 in obesity-induced liver cancer, Control of Lipogenesis and Hepatic Steatosis by Caspase-2, Diabetes Research Center (DRC)

OpenAlex ID: W2890819762

FWCI: 17.92

Cites: 59

Cited by: 340

Related to: 10