Year: 2017
Type: article
Abstract: Traditional contrast agents use inorganic compounds containing metal ions to differentiate tissue types in medical diagnostic imaging. These compounds suffer from toxicity and they do not target specific tissues. A human serum albumin and gold complex (Au@HSA) was synthesized via a biomineralization reaction to overcome these obstacles and the resulting compound was optically active, giving it potential as a contrast agent. Additionally, the Au@HSA was conjugated with the tumor targeting compound arginylglycylaspartic acid without losing its optical activity.
Source: Digital WPI
Author: Sarah K. Fields
Language: Finnish
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2891292889
