Investigation of Nerve Conduction in Patients with Diabetes and/or Hemodialysis
Year: 2017
Type: article
Study design: Observational Study
Abstract: Diabetic peripheral neuropathy (DPN) has been clinically important, and nerve conduction studies (NCS) have been performed with rather complexity and high cost. By advances in technology, simple and useful DPN-Check device was developed obtaining NCS data as sural nerve conduction velocity (SNCV) and sural nerve action potential (SNAP). We enrolled 52 subjects classified into 4 groups according to the presence of hemodialysis (HD) and diabetes mellitus (DM) as follows: HD (+), DM (+) in group 1, HD (+), DM (-) in group 2, HD (-), DM (+) in group 3 and healthy controls in group 4. Average age was similar from 68 to 74 years in 4 groups. Median value of SNCV was 31, 48, 49, 54 m/sec, and median value of SNAP was 3, 9, 6, 22 μV, respectively, in 4 groups. These results might suggest some relationship between impaired states of HD and DM, and would become fundamental data for pathophysiological investigation of peripheral neuropathy of HD and/or DM in the future.
Authors: Tomomi Fujikawa, Yoshikane Kato, Hiroshi Bando, Miyuki Narutaki, Masami Yamamoto, Hideki Kakutani, Yujiro Shirai, Kazuyo Ishikura, Kazuhiro Kusunoki, Saeka Tanaka, Takafumi Kawata, Setsuko Kanazawa, Sayuri Matsuzaki, Masahiro Bando, Shinnichi Waka
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2891409681