Work

Increased 30-Day Mortality Associated With Carbapenem-Resistant Enterobacteriaceae in Children

Year: 2018

Type: article

Study design: Observational Study

Abstract: In this multicenter study, we identified an increased risk of 30-day mortality among hospitalized children with carbapenem-resistant Enterobacteriaceae (CRE) isolated from clinical cultures compared with those with carbapenem-susceptible Enterobacteriaceae. We additionally report significant variation in antibiotic treatment for children with CRE infections with infrequent use of combination therapy.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofy222

Authors: Kathleen Chiotos, Pranita D Tamma, Kelly B Flett, Manjiree V Karandikar, Koorosh Nemati, Warren B Bilker, Theoklis Zaoutis, Jennifer H Han

Institutions: Children's Hospital of Philadelphia, Johns Hopkins University, Johns Hopkins Medicine, Boston Children's Hospital, University of Pennsylvania

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funders: Centers for Disease Control and Prevention, National Institute of Allergy and Infectious Diseases, National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: G291771686, Carbapenem-Resistant Klebsiella Pneumoniae in Long-Term Acute Care Hospitals, G5233640899, Pediatric Hospital Epidemiology and Outcomes Research Training Program, The Use of MALDI TOF for the Rapid Detection of Carbapenemases from Clinical Isolates

OpenAlex ID: W2891457461

FWCI: 1.888

Cites: 12

Cited by: 51

Related to: 10