Work

Combining stereotactic body radiation therapy with immunotherapy: current data and future directions

Year: 2018

Type: article

Abstract: Stereotactic body radiation therapy (SBRT) offers excellent local control of early-stage non-small cell lung cancer (NSCLC), but there currently is a need for tolerable systemic therapy to address regional and distant disease progression. One potential option is immunotherapy, which in metastatic NSCLC has shown promise for sustained disease control in a subset of patients. There is also growing evidence for a clinical synergy between radiation and immunotherapy, with several ongoing trials studying the abscopal effect. This review summarizes the current data in the fast-changing field of immuno-radiation therapy, highlighting updates from recent clinical trials.

Source: Translational Lung Cancer Research

DOI: 10.21037/tlcr.2018.08.16

Authors: Alexander J. Lin, Michael Roach, Jeffrey Bradley, Clifford Robinson

Institutions: Washington University in St. Louis, Alvin J. Siteman Cancer Center

Language: English

Topic: Lung Cancer Diagnosis and Treatment

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2891532865

FWCI: 4.071

Cites: 64

Cited by: 51

Related to: 10