The Neural Substrate of Reward Anticipation in Health: A Meta-Analysis of fMRI Findings in the Monetary Incentive Delay Task
Year: 2018
Type: review
Study designs: Systematic Review, Meta-Analysis
Abstract: The monetary incentive delay task breaks down reward processing into discrete stages for fMRI analysis. Here we look at anticipation of monetary gain and loss contrasted with neutral anticipation. We meta-analysed data from 15 original whole-brain group maps (n = 346) and report extensive areas of relative activation and deactivation throughout the whole brain. For both anticipation of gain and loss we report robust activation of the striatum, activation of key nodes of the putative salience network, including anterior cingulate and anterior insula, and more complex patterns of activation and deactivation in the central executive and default networks. On between-group comparison, we found significantly greater relative deactivation in the left inferior frontal gyrus associated with incentive valence. This meta-analysis provides a robust whole-brain map of a reward anticipation network in the healthy human brain.
Source: Neuropsychology Review
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,890
Awards: King's Health Partners Confidence in Concept, CANNABIDIOL AS A NOVEL THERAPEUTIC AGENT FOR PATIENTS AT ULTRA HIGH-RISK OF PSYCHOSIS: AN EXPERIMENTAL MEDICINE APPROACH, Placebo Effects in Depression: Towards the Validation of Biomarkers, Neurochemical Endophenotype Responses to Pain-Stress, Prediction of Risk of Relapse of Psychosis - Examining the Interaction Between Genes and Substance Use (PREDICT), Trajectory of Brain Structure and Function before and after the Onset of Psychosis: a Longitudinal Multicentre Study
OpenAlex ID: W2892840228