Transcranial Direct Current Stimulation for Poststroke Motor Recovery: Challenges and Opportunities
Year: 2018
Type: review
Abstract: There has been a renewed research interest in transcranial direct current stimulation (tDCS) as an adjunctive tool for poststroke motor recovery as it has a neuro-modulatory effect on the human cortex. However, there are barriers towards its successful application in motor recovery as several scientific issues remain unresolved, including device-related issues (ie, dose-response relationship, safety and tolerability concerns, interhemispheric imbalance model, and choice of montage) and clinical trial-related issues (ie, patient selection, timing of study, and choice of outcomes). This narrative review examines and discusses the existing challenges in using tDCS as a brain modulation tool in facilitating recovery after stroke. Potential solutions pertinent to using tDCS with the goal of harnessing the brains plasticity are proposed.
Source: PM&R
Language: English
Subfield: Neurology
Field: Neuroscience
Domain: Life Sciences
Open Access status: bronze
Funders: U.S. Department of Veterans Affairs, American Heart Association, National Institutes of Health, National Institute of Mental Health, National Institute of General Medical Sciences, National Institute of Neurological Disorders and Stroke, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: Imaging the Neural Effects of Transcranial Direct Current Stimulation, South Carolina Collaborative Alliance for Stroke Trials (SC-CoAST), G2846156425, National Center of Neuromodulation for Rehabilitation (NC NM4R), COBRE in Stroke Recovery, TRANScranial direct current stimulation for POst-stroke motor Recover - a phase II sTudy (TRANSPORT 2), Stroke Trials Network National Data Management Center (NDMC)
OpenAlex ID: W2893070407