Genetic Risk of Alzheimer’s Disease: Three Wishes Now That the Genie is Out of the Bottle
Year: 2018
Type: article
Abstract: The availability and increasing popularity of direct-to-consumer genetic testing for the presence of an APOE4 allelle led the Alzheimer's Foundation of America Medical, Scientific and Memory Screening Advisory Board to identify three critical areas for attention: 1) ensure consumer understanding of test results; 2) address and limit potential negative consequences of acquiring this information; and 3) support linking results with positive health behaviors, including potential clinical trial participation. Improving access to appropriate sources of genetic counseling as part of the testing process is critical and requires action from clinicians and the genetic testing industry. Standardizing information and resources across the industry should start now, with the input of consumers and experts in genetic risk and health information disclosure. Direct-to-consumer testing companies and clinicians should assist consumers by facilitating consultation with genetic counselors and facilitating pursuit of accurate information about testing.
Source: Journal of Alzheimer s Disease
DOI: 10.3233/jad-180629
Institutions: American Political Science Association, Patient-Centered Outcomes Research Institute, VA Palo Alto Health Care System, Stanford University, University of Minnesota, University of Washington, Albert Einstein College of Medicine, University of South Florida, Cleveland Clinic, Lou Ruvo Brain Institute, Feinstein Institute for Medical Research, Texas Tech University Health Sciences Center, University of Chicago, University of Chicago Medical Center, Mercer University, The University of Texas at San Antonio, University of Alabama, University of Alabama at Birmingham, UAB Medicine, University of Kentucky
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Funder: National Institute on Aging
Award: G384347443
OpenAlex ID: W2893887360