Work

Unusual Case of Lipoprotein Glomerulopathy First Diagnosed in a Protocol Kidney Allograft Biopsy

Year: 2018

Type: article

Abstract: Lipoprotein glomerulopathy (LPG) is caused by mutations in APOE, the gene encoding apolipoprotein E. The most commonly encountered mutations are APOE Sendai (p.Arg145Cys), APOE Kyoto (p.Arg25Cys or p.Arg43Cys), and APOE Tokyo (p.Leu141_Lys143del or p.Arg142_Leu144del), whose names correspond to the cities in which the index patients lived.1 Most cases have been reported from East Asian countries; only a few cases from the United States have been described.2 We present a case of LPG that was first diagnosed in a protocol kidney allograft biopsy.

Source: Kidney International Reports

DOI: 10.1016/j.ekir.2018.09.020

Authors: Ibrahim Batal, Gaia Fakhoury, Emily Groopman, Vivette D. D’Agati, Heather Morris

Institution: Columbia University Irving Medical Center

Language: English

Topic: Renal Diseases and Glomerulopathies

Subfield: Nephrology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,800