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CD133 Expression in Glioblastoma Multiforme: A Literature Review

Year: 2018
Type: article
Abstract: Glioblastoma, also known as glioblastoma multiforme (GBM), is the most common primary brain tumor. Extensive research has been carried out to discover the factors associated with the course and progression of GBM. CD133 is a glycoprotein antigen found in normal and malignant tissues. CD133 has been recognized as a marker for the growth of cancer cells. The association between this tissue marker and GBM is being investigated. The aim of this review was to evaluate the role of CD133 as a tumor marker for the prognosis of GBM.
Source: Cureus
DOI: 10.7759/cureus.3439
Authors: Syed Ijlal Ahmed, Gohar Javed, Altaf Ali Laghari, Syeda Beenish Bareeqa, Saba Farrukh, Shajeeah Zahid, Syeda Sana Samar, Kashif Aziz
Institutions: Aga Khan University, Liaquat National Hospital, Jinnah Sindh Medical University, Jinnah Medical & Dental College, Queens Hospital Center, Icahn School of Medicine at Mount Sinai, Mount Sinai Queens
Language: English
Subfield: Oncology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W2895913993
FWCI: 1.479
Cites: 29
Cited by: 38
Related to: 10