Work

Build a Bank: Off-the-Shelf Virus-Specific T Cells

Year: 2018

Type: article

Abstract: Viral infections remain a major complication after hematopoietic stem cell transplantation (HSCT); however, over the past 25 years, investigators around the world have shown that ex vivo-expanded virus-specific T cells (VSTs) are an attractive option for refractory cytomegalovirus (CMV), Epstein-Barr virus (EBV), and adenoviral infections and for various other transplantation-related viruses. Recent advances in this approach, such as activated T cell and multimer selection, have reduced the time required from 2 to 3 months to overnight [1].

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2018.10.010

Author: Patrick J. Hanley

Institutions: Children's National, George Washington University

Language: English

Topic: Cytomegalovirus and herpesvirus research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650