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Autism and Probable Prerequisites: Severe and Scheduled Prenatal Stresses at Spotlight.

Year: 2018

Type: article

Abstract: BACKGROUND: Due to the importance of prenatal maternal stress as environmental factor on autism, the influence of prenatal maternal psychological agitations was assessed in relation with the risk of autism. METHODS: In this case-control study, some mothers of autistic children in Isfahan, central Iran, in 2014, were retrospectively compared with control mothers in terms of quantity, quality, and schedule of exposure to 45 stressful events in a 15-month period. In addition, dividing the stressors into two groups of genome-dependent/independent events, their prevalence was separately scrutinized and compared among patient and control families. RESULTS: =0.000), but genome-dependent events led to more stress inpatient families. CONCLUSION: Although the present study consistent with recent findings in the fields of epigenetics and gene-environment interactions can confirm the role of severe and scheduled prenatal stresses in causing autism, it does not deny the necessity of a perspective and wider study in Isfahan and Iran.

Source: Europe PMC (PubMed Central)

Authors: Seyyed Mohammad Mousavi, Elahe Kamali, Fatemeh Fatahi, Hadi Babaie, Mansoor Salehi

Institutions: Shahrekord University of Medical Sciences, University of Isfahan, Isfahan University of Medical Sciences

Language: English

Topic: Autism Spectrum Disorder Research

Subfield: Cognitive Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2896439254

FWCI: 0.137

Cites:

Cited by: 3

Related to: 10