Spatial and temporal coordination of antiviral responses by group 1 ILC s
Year: 2018
Type: review
Abstract: Group 1 innate lymphocytes consist of a phenotypically, spatially, and functionally heterogeneous population of NK cells and ILC1s that are engaged during pathogen invasion. We are only beginning to understand the context-dependent roles that different subsets of group 1 innate lymphocytes play during homeostatic perturbations. With a focus on viral infection, this review highlights the organization and regulation of spatially and temporally distinct waves of NK cell and ILC1 responses that collectively serve to achieve optimal viral control.
Source: Immunological Reviews
DOI: 10.1111/imr.12710
Authors: Nicholas M. Adams, Joseph C. Sun
Language: English
Topic: IL-33, ST2, and ILC Pathways
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
Awards: G2653245347, Regulation of Nfil3 in innate lymphocyte-mediated host immunity, Elucidating the function of IRF8 during antiviral natural killer cell responses, G76496126, Weill Cornell/Rockefeller/Sloan Kettering MST Program, Cancer Center Support Grant, The natural killer cell response against mouse cytomegalovirus infection
OpenAlex ID: W2896453461