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Nocturnal Hypoxemia, But Not Sleep Apnea, Is Associated With a Poor Prognosis in Patients With Pulmonary Arterial Hypertension

Year: 2018

Type: article

Abstract: BACKGROUND: Sleep apnea (SA) can cause repeated nocturnal arterial oxygen desaturation and result in acute increase in pulmonary arterial pressure (PAP). The presence of SA is associated with a poor prognosis in patients with chronic left-sided heart failure, but little is known for patients with pulmonary arterial hypertension (PAH). METHODS AND RESULTS: =14.7, P<0.001) and that was the only independent variable related to death in multivariate Cox proportional hazards analysis. CONCLUSIONS: SA in patients with PAH was not associated with worse prognosis, unlike left ventricular heart failure, but nocturnal hypoxemia was related to poor prognosis.

Source: Circulation Journal

DOI: 10.1253/circj.cj-18-0636

Authors: Mika Nagaoka, Ayumi Goda, Kaori Takeuchi, Hanako Kikuchi, Mayumi Finger, Takumi Inami, Kyoko Soejima, Toru Satoh

Institutions: Kyorin University, Kyorin University Hospital

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W2896471252

FWCI: 1.984

Cites: 24

Cited by: 45

Related to: 10