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Cover Feature: Mechanical Cooperativity in DNA Cruciform Structures (ChemPhysChem 20/2018)

Year: 2018

Type: article

Abstract: The Cover Feature shows a Chinese knot (left) that represents an interwinding DNA cruciform structure (background). At positive template superhelicities, mechanical cooperativity in a DNA cruciform strengthens its mechanical stability, which is depicted by its capability to hold a heavier lock than that sustained by a regular structure without mechanical cooperativity (right). More information can be found in the Article by S. Manda et al. on page 2627 in Issue 20, 2018 (DOI: 10.1002/cphc.201800480).

Source: ChemPhysChem

DOI: 10.1002/cphc.201800843

Authors: Shankar Mandal, Sangeetha Selvam, Yunxi Cui, Mohammed Enamul Hoque, Hanbin Mao

Institutions: Kent State University, Nankai University, State Key Laboratory of Medicinal Chemical Biology

Language: English

Topic: DNA and Nucleic Acid Chemistry

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

OpenAlex ID: W2897024828

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