Work

Inhibition of AURKA Reduces Proliferation and Survival of Gastrointestinal Cancer Cells With Activated KRAS by Preventing Activation of RPS6KB1

Year: 2018

Type: article

Source: Gastroenterology

DOI: 10.1053/j.gastro.2018.10.030

Authors: Lihong Wang-Bishop, Zheng Chen, Ahmed Gomaa, Albert Craig Lockhart, Safia Salaria, Jialiang Wang, Keeli B. Lewis, Jeffrey Ecsedy, Kay Washington, Robert Daniel Beauchamp, Wael El-Rifai

Institutions: Vanderbilt University, University of Miami, Sylvester Comprehensive Cancer Center, Vanderbilt University Medical Center, Takeda Oncology (United States), University of Miami Health System, Miami VA Healthcare System

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, Vanderbilt University, University of Miami, Sylvester Comprehensive Cancer Center, University of Miami Health Systems, National Institutes of Health, Leonard M. Miller School of Medicine, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G2065299061, G702371463, The Role of Aurora Kinase in Upper Gastrointestinal Adenocarcinomas, G8710842620, Molecular and Cellular Basis for Digestive Diseases, Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal Cancer

OpenAlex ID: W2897103727

FWCI: 4.571

Cites: 50

Cited by: 93

Related to: 10