Work

Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery

Year: 2018

Type: review

Abstract: The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of engineered-exosomes or exosome-mimetics, which may be artificial (liposomal) or cell-derived vesicles, as advanced platforms for targeted drug delivery. Here, we provide the current state-of-the-art of using exosome or exosome-inspired systems for drug delivery. We review the various approaches investigated and the shortcomings of each approach. Finally the challenges which have been identified to date in this field are summarized.

Source: Pharmaceutics

DOI: 10.3390/pharmaceutics10040218

Authors: Sophia G. Antimisiaris, Spyridon Mourtas, Antonia Marazioti

Institutions: University of Patras, Foundation for Research and Technology Hellas

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,499