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Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease

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Year: 2018
Type: article
Source: Journal of Molecular Medicine
DOI: 10.1007/s00109-018-1703-0
Authors: Yuehong Chen, Jinlong Jian, Aubryanna Hettinghouse, Xueheng Zhao, Kenneth D. R. Setchell, Ying Sun, Chuan-ju Liu
Institutions: Sichuan University, NYU Langone Health, West China Hospital of Sichuan University, New York University, Cincinnati Children's Hospital Medical Center
Language: English

Topic: Lysosomal Storage Disorders Research
Subfield: Physiology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Defense, China Scholarship Council, National Institutes of Health, National Institute of Neurological Disorders and Stroke, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: DEVELOPING PROGRANULIN-LOADED PROTEIN ENGINEERED HYDROGEL FOR POST-TRAUMATIC OSTEOARTHRITIS, The immunological mechanism of PGRNs anti-inflammatory effect, The Role of PGRN Growth Factor in Osteoarthritis. - Renewal - 1, G6952421091, Progranulin: A Novel Gene in Gaucher Diseases
OpenAlex ID: W2897819547
FWCI: 3.431
Cites: 56
Cited by: 45
Related to: 10
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