Work

A chemoselective strategy for late-stage functionalization of complex small molecules with polypeptides and proteins

Year: 2018

Type: article

Source: Nature Chemistry

DOI: 10.1038/s41557-018-0154-0

Authors: Daniel T. Cohen, Chi Zhang, Colin M. Fadzen, Alexander J. Mijalis, Liana Hie, Kenneth D. Johnson, Zachary Shriver, Obadiah Plante, Scott J. Miller, Stephen L. Buchwald, Bradley L. Pentelute

Institutions: AbbVie (United States), Massachusetts Institute of Technology, Yale University, Visterra (United States), Broad Institute, Harvard University

Language: English

Topic: Chemical Synthesis and Analysis

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, National Institute of General Medical Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Awards: Chemically Modified Peptide Agents for Next-Generation Conjugate Therapies to Treat Duchenne Muscular Dystrophy, Development of Site-Selective Glycosylation of Unprotected Sugars, Site-Selective Catalysis for Organic Synthesis, CATALYTIC METHODS FOR ORGANIC SYNTHESIS, Acquisition of Octet Biolayer Interferometry system for MIT biophysics facility, Development of New Metal_Catalyzed Hydroacylation and Hydroarylation Processes, Cysteine Arylation, Catalytic Methods for Organic Synthesis, Metal-Catalyzed Methods for Organic Synthesis

OpenAlex ID: W2898863862

FWCI: 4.711

Cites: 37

Cited by: 100

Related to: 10