Year: 2018
Type: editorial
Abstract: ulmonary hypertension (PH) or elevated blood pressure in the pulmonary vasculature is a serious disease entity in its own right and a grave complication of other disorders.PH is divided into 5 classes by the World Health Organization.Class 1, or pulmonary artery hypertension (PAH), includes PH due to idiopathic, heritable, and genetic causes, as well as drugs, toxins, and some connective tissue diseases and infections.Unfortunately, PAH is lethal, with one-half of all patients dying within 7 years of their initial diagnosis (1).The pathophysiology of PH is complex, with an intricate interplay among diverse cell types, including smooth muscle cells, endothelial cells, fibroblasts, inflammatory cells, and neurons (2-6).Undoubtedly, this complexity
Authors: Aglaia Ntokou, Daniel M. Greif
Institution: Yale University
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $4,750
OpenAlex ID: W2898988886