Nanoproteomics comes of age
Year: 2018
Type: review
Abstract: INTRODUCTION: Nanoproteomics, which is defined as quantitative proteome profiling of small populations of cells (<5000 cells), can reveal critical information related to rare cell populations, hard-to-obtain clinical specimens, and the cellular heterogeneity of pathological tissues. Areas covered: We present a brief review of the recent technological advances in nanoproteomics. These advances include new technologies or approaches covering major areas of proteomics workflow ranging from sample isolation, sample processing, high-resolution separations, to MS instrumentation. Expert commentary: We comment on the current state of nanoproteomics and discuss perspectives on both future technological directions and potential enabling applications.
Source: Expert Review of Proteomics
Language: English
Subfield: Spectroscopy
Field: Chemistry
Domain: Physical Sciences
Open Access status: green
Awards: High-throughput multidimensional bioseparations for next-generation proteomics, Area A: In-Depth Proteome Mapping of the Tumor Microenvironment with Single- Cell Resolution, Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Serum protein biomarkers for predicting type 1 diabetes
OpenAlex ID: W2899038378