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Tranexamic acid mediates proinflammatory and anti-inflammatory signaling via complement C5a regulation in a plasminogen activator–dependent manner

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Year: 2018
Type: article
Source: The Journal of Trauma: Injury, Infection, and Critical Care
DOI: 10.1097/ta.0000000000002092
Authors: Christopher D. Barrett, Hunter B. Moore, Yi-Wen Kong, Michael P. Chapman, Ganapathy Sriram, Dan Lim, Ernest E. Moore, Michael B. Yaffe
Institutions: Beth Israel Deaconess Medical Center, Harvard University, Koch Institute for Integrative Cancer Research At MIT, Massachusetts Institute of Technology, University of Colorado Denver, Denver Health Medical Center
Language: English

Topic: Complement system in diseases
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Heart, Lung, and Blood Institute, National Institute of General Medical Sciences
Awards: The Coagulopathy-Inflammation Interface: Integration of Coagulopathy and Complement Activation as a Mechanism for Neutrophil Priming and Tissue Damage, G5300963347, Analysis and Characterization of Trauma-Induced Coagulopathy
OpenAlex ID: W2899288620
FWCI: 2.469
Cites: 35
Cited by: 76
Related to: 10
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