Work

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures

Year: 2018

Type: review

Source: Nature Reviews Drug Discovery

DOI: 10.1038/nrd.2018.180

Authors: Ichio Shimada, Takumi Ueda, Yutaka Kofuku, Matthew T. Eddy, Kurt Wüthrich

Institutions: The University of Tokyo, University of Southern California, Scripps Research Institute, University of Florida

Language: English

Topic: Receptor Mechanisms and Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Japan Society for the Promotion of Science, National Institute of General Medical Sciences

Awards: Development of methods for studying conformational dynamics of ubiquitin-ubiquitin binding protein complex, Structural basis of signal transduction mediated by various GPCRs, Dynamics of the Opioid Receptor Signaling Complex, In situ functional analyses of membrane proteins by NMR

OpenAlex ID: W2899596245

FWCI: 2.89

Cites: 278

Cited by: 281

Related to: 10