A Novel Multi-dimensional Multimorbidity Index: Results From the Baltimore Longitudinal Study of Aging
Year: 2018
Type: conference-abstract
Abstract: Although the incidence and prevalence of multimorbidity(MM) have surged, there is no consensus on an optimal tool to measure MM as a risk factor for functional decline or as an outcome. Most of the available tools have been developed based on medical reports, hospital administrative records or self-reports. In this study, we assessed a novel tool developed from repeated measures of clinical data collected in the Baltimore Longitudinal Study of Aging. In 900 participants, aged 50–100 years with an average follow-up of 4.5 years, we assessed organ-specific medical examinations and medication use to develop a rigorous index that captures time-dependent accumulative MM effects on accelerated aging. A weighted index using longitudinal data provides a time-dependent weighted association, a novel multi-dimensional index that significantly predicts accelerated age-related adverse outcomes.
Source: Innovation in Aging
Authors: S Salimi, L Ferrucci, J Guralnik
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $3,977
OpenAlex ID: W2899729136