Work

Canary in the Coal Mine? Transmitted Mutations Conferring Resistance to All Integrase Strand Transfer Inhibitors in a Treatment-Naive Patient

Year: 2018

Type: article

Abstract: Transmitted drug resistance to the integrase strand transfer inhibitor (INSTI) class of antiretrovirals is very rare. We present a case of a treatment-naive female patient with human immunodeficiency virus harboring resistance to all INSTIs, including bictegravir and dolutegravir.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofy294

Authors: Kara S McGee, Nwora Lance Okeke, Christopher B Hurt, Mehri S McKellar

Institutions: Duke Medical Center, University of North Carolina at Chapel Hill

Language: English

Topic: HIV/AIDS drug development and treatment

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053