Work

Successful rebuilding after disaster, even in the heart, starts with infrastructure

Year: 2018

Type: article

Abstract: Mammalian heart regeneration has been the subject of intense debate and investigation among cardiovascular scientists for more than a century (1). While it is now widely accepted that the mammalian heart does have the capacity for self-renewal, replacement of injured tissue with new cardiomyocytes happens at a very low rate in the adult heart, and is not sufficient for the recovery of cardiac function after massive loss of cells (2).

Source: Journal of Thoracic Disease

DOI: 10.21037/jtd.2018.10.95

Authors: Michael P. Robich, Sergey Ryzhov, Douglas B. Sawyer

Institutions: Maine Medical Center, Maine Medical Center, Maine Medical Center Research Institute

Language: English

Topic: Congenital heart defects research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute of General Medical Sciences