Work

Transient activation of the UPR ER is an essential step in the acquisition of pluripotency during reprogramming

Year: 2019

Type: article

Abstract: A transient activation of the unfolded protein response of the ER is a key factor of cellular reprogramming success.

Source: Science Advances

DOI: 10.1126/sciadv.aaw0025

Authors: Milos S. Simic, Erica Moehle, Robert T. Schinzel, Franziska Lorbeer, Damien Jullié, Jonathan J. Halloran, Kartoosh Heydari, Melissa Sanchez, Dirk Hockemeyer, Andrew Dillin

Institutions: Howard Hughes Medical Institute, California Institute for Regenerative Medicine, University of California, Berkeley, University of California, San Francisco

Language: English

Topic: Pluripotent Stem Cells Research

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,500

Funders: Howard Hughes Medical Institute, California Institute for Regenerative Medicine, National Institutes of Health, National Institute on Aging, National Cancer Institute

Awards: Cell non-autonomous function of the unfolded protein response, A Requirement for Protein Homeostasis in the Mediation of Stem Cell Health, Telomerase function in human tumor and stem cell biology

OpenAlex ID: W2951893167

FWCI: 1.885

Cites: 39

Cited by: 36

Related to: 10