Vascular Aging Is Accelerated in Flight Attendants With Occupational Secondhand Smoke Exposure
Year: 2018
Type: article
Study design: Observational Study
Abstract: OBJECTIVE: To determine whether early vascular aging may be present in flight attendants with remote in-cabin secondhand smoke (SHS) exposure. METHODS: Twenty-six flight attendants with a history of in-cabin SHS exposure prior to the airline smoking bans were recruited. Pulse wave analysis, peripheral arterial tonometry, and brachial artery reactivity testing evaluated their arterial compliance and endothelial function. RESULTS: Flight attendants with remote in-cabin SHS exposure have normal blood pressure, pulse wave velocity, and reactive hyperemia index, but abnormal pulse pressure, augmentation index, flow-mediated dilation, and hyperemic mean flow ratio. CONCLUSION: These preliminary findings suggest that flight attendants with remote in-cabin SHS exposure have preclinical signs of accelerated vascular aging and raise new questions about the relationship between remote SHS exposure and vascular health.
Authors: Janet Wei, Chrisandra Shufelt, Eveline Oestreicher Stock, Claire Mills, Shivani Dhawan, Riya Jacob, Tina Torbati, Galen Cook-Wiens, Neal Benowitz, Peyton Jacob, Peter Ganz, Cathleen Noel Bairey Merz, Rita Redberg
Institutions: Cedars-Sinai Medical Center, San Francisco General Hospital, National Institute on Drug Abuse, University of California, San Francisco, Flight Attendant Medical Research Institute, University of California System, University of California San Francisco Medical Center, Cedars-Sinai Smidt Heart Institute
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2901492878