Nanoparticle-Templated Self-Assembly of Viral Capsids Probed by Time-Resolved Absorbance Spectroscopy and X-Ray Scattering
Year: 2018
Type: article
Abstract: The stabilization of gold nanoparticles by biocompatible agents is crucial to their use in theranostics and biomedical imaging. Viral capsids can efficiently encapsulate gold nanoparticles, but the kinetic pathways of this multiscale, spatiotemporal process remain elusive. The authors use time-resolved absorbance spectroscopy and x-ray scattering to elucidate a three-step mechanism with timescales that span four orders of magnitude. This work highlights the robustness, adaptability, and utility of viral proteins, and should promote further studies of bioinspired systems.
Source: Physical Review Applied
Authors: Andrew Burke, Maelenn Chevreuil, Alisier Paris, Vanessa de La Grange, Claire Goldmann, Javier Pérez, Doru Constantin, Guillaume Tresset
Language: English
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
OpenAlex ID: W2902121913