Using DNA to predict educational trajectories in early adulthood.
Year: 2019
Type: article
Study design: Observational Study
Abstract: At the end of compulsory schooling, young adults decide on educational and occupational trajectories that impact their subsequent employability, health and even life expectancy. To understand the antecedents to these decisions, we follow a new approach that considers genetic contributions, which have largely been ignored before. Using genomewide polygenic scores (EA3) from the most recent genomewide association study of years of education in 1.1 million individuals, we tested for genetic influence on early adult decisions in a United Kingdom-representative sample of 5,839 at 18 years of age. EA3 significantly predicted educational trajectories in early adulthood (Nagelkerke R2 = 10%), χ2(4) = 571.77, p < .001, indicating that young adults partly adapt their aspirations to their genetic propensities-a concept known as gene-environment correlation. Compared to attending university, a 1 standard deviation increase in EA3 was associated on average with a 51% reduction in the odds of pursuing full-time employment (OR = .47; 95% CI [.43, .51]); an apprenticeship (OR = .49; 95% CI [.45, .54]); or not going in education, employment, or training (OR = .50; 95% CI [.41, .60]). EA3 associations were attenuated when controlling for previous academic achievement and family socioeconomic status. Overall this research illustrates how DNA-based predictions offer novel opportunities for studying the sociodevelopmental structures of life outcomes. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
Source: Developmental Psychology
DOI: 10.1037/dev0000682
Authors: Ziada Ayorech, Robert Plomin, Sophie von Stumm
Institutions: King's College London, University of York
Language: English
Subfield: Sociology and Political Science
Field: Social Sciences
Domain: Social Sciences
SDG: Quality education
Open Access status: green
Awards: G2496263360, G2761558319, G4449678476, Aggression in Children: Unraveling gene-environment interplay to inform Treatment and InterventiON strateg, G4590952238, G463724992, Origins of learning difficulties and behaviour problems: from behavioural genetics to behavioural genomics., G4921234783, G536866722, Colorado Adoption Project/Twin Study of Lifespan behavioral development & cognitive aging [CATSLife2], G7624716486, G7716769900, G8658852833
OpenAlex ID: W2902341087
