Get started
Work

The good, the bad, and the ugly of calcium supplementation: a review of calcium intake on human health

Year: 2018
Type: article
Abstract: Calcium is an important integrative component of the human body and critical for human health. It has been well established that calcium intake is helpful in the prevention and treatment of osteoporosis, which has become one of the most serious public health problems across the world. However, community-dwelling adults with and without osteoporosis are rarely concerned or even not aware of the potential side effects of high or inappropriate doses of calcium intake. Some recent studies have revealed that excessive calcium intake might increase the risks of cardiovascular diseases. The purpose of this article was to review the health benefits, costs, and consequences of calcium supplementation on osteoporosis/osteoporotic fractures, cardiovascular events, kidney stones, gastrointestinal diseases, and other important diseases. In the end, we suggest that calcium supplementation should be prescribed and taken cautiously, accounting for individual patients' risks and benefits. Clearly, further studies are needed to examine the health effects of calcium supplementation to make any solid recommendations for people of different genders, ages, and ethnicities.
DOI: 10.2147/cia.s157523
Authors: Kelvin Li, Xia-Fang Wang, Ding-You Li, Yuan-Cheng Chen, Lan-Juan Zhao, Xiao-Gang Liu, Yan-Fang Guo, Jie Shen, Xu Lin, Jeffrey Deng, Rou Zhou, Hong-Wen Deng
Institutions: Tulane University, Third Affiliated Hospital of Southern Medical University, Children's Mercy Hospital, University of Missouri–Kansas City, Xi'an Jiaotong University, Southern Medical University, Central South University, National Clinical Research, Xiangya Hospital Central South University
Language: English
Field: Medicine
Open Access status: gold
Estimated APC paid: $2,836
Funders: Tulane University, National Institutes of Health, National Institute on Aging, National Institute of Mental Health, National Institute of General Medical Sciences, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: G19956286, Integration of brain imaging with genomic and epigenomic data, Epigenomewide DNA Methylation Study for Osteoporosis Risk, Decoding Methylation Mediated Epigenomic Contributions to Male Osteoporosis, G571018580, Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases, Trans-omics Integration of Multi-omics Studies for Osteoporosis
OpenAlex ID: W2902969078
FWCI: 9.916
Cites: 79
Cited by: 199
Related to: 10