A Transethnic Mendelian Randomization Study Identifies Causality of Obesity on Risk of Psoriasis
Year: 2018
Type: article
Study design: Observational Study
Abstract: Psoriasis is a chronic disorder characterized by cutaneous and systemic manifestations. Epidemiological studies have reported increased comorbidity of psoriasis with numerous complex diseases such as metabolic clinical measurements (Greb et al., 2016; Naito and Imafuku, 2016). However, interpretation of the comorbidity remains controversial to date, because causal inference between correlated phenotypes is difficult when depending solely on epidemiological studies. Identification of causal inference between correlated phenotypes has significant clinical impacts, because modification of the causal phenotypes could benefit treatment of the outcome phenotypes.
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,800
Awards: Identification of Psoriatic Arthritis Genes, Linkage Analysis of Familial Psoriasis, Risk stratification and subtype classification of type 2 diabetes from disease genome by machine learning, G4726403787, Functional Genomics of Psoriasis, G6308906652, Genetic and Genomic Dissection of Psoriatic Arthritis, G7531793261, General Clinical Research Center, Development of the novel drug repositioning method based on disease genetics, Identification of biomarkers of autoimmune diseases using HLA imputation
OpenAlex ID: W2903033907