Work

Dynamics of deformable straight and curved prolate capsules in simple shear flow

Year: 2019

Type: article

Abstract: increases weakly as the degree of curvature increases but shows negligible dependency on deformability. These features are not changed substantially as the viscosity ratio between the inner and outer fluids is changed from 1 to 5. As cell deformability, cell shape, and cell-cell interactions are all pathologically altered in blood disorders such as SCD, these results will have clear implications on improving our understanding of the pathophysiology of hematologic disease.

Source: Physical Review Fluids

DOI: 10.1103/physrevfluids.4.043103

Authors: Xiao Zhang, Wilbur A. Lam, Michael D. Graham

Institutions: University of Wisconsin–Madison, Georgia Institute of Technology, Emory University, The Wallace H. Coulter Department of Biomedical Engineering, Children's Healthcare of Atlanta, Winship Cancer Institute

Language: English

Topic: Blood properties and coagulation

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

Open Access status: green

Funders: National Science Foundation, National Institutes of Health, Division of Chemical, Bioengineering, Environmental, and Transport Systems, National Institute on Minority Health and Health Disparities

Awards: Cell distribution and segregation phenomena in blood flow: biomechanical aspects and impacts, G7765923520, Leveraging microfluidic technologies and cell-scale simulations to investigate sickle cell vasculopathy

OpenAlex ID: W2903167729

FWCI: 1.263

Cites: 58

Cited by: 12

Related to: 10