Amyotrophic lateral sclerosis–specific quality of life–short form (ALSSQOL‐SF): A brief, reliable, and valid version of the ALSSQOL‐R
Year: 2018
Type: article
Abstract: INTRODUCTION: The Amyotrophic Lateral Sclerosis (ALS)-Specific Quality of Life instrument and its revised version (ALSSQOL and ALSSQOL-R) have strong psychometric properties, and have demonstrated research and clinical utility. In this study we aimed to develop a short form (ALSSQOL-SF) suitable for limited clinic time and patient stamina. METHODS: The ALSSQOL-SF was created using Item Response Theory and confirmatory factor analysis on 389 patients. A cross-validation sample of 162 patients assessed convergent, divergent, and construct validity of the ALSSQOL-SF compared with psychosocial and physical functioning measures. RESULTS: The ALSSQOL-SF consisted of 20 items. Compared with the ALSSQOL-R, optimal precision was retained, and completion time was reduced from 15-25 minutes to 2-4 minutes. Psychometric properties for the ALSSQOL-SF and its subscales were strong. DISCUSSION: The ALSSQOL-SF is a disease-specific global QOL instrument that has a short administration time suitable for clinical use, and can provide clinically useful, valid information about persons with ALS. Muscle Nerve 58: 646-654, 2018.
Source: Muscle & Nerve
DOI: 10.1002/mus.26203
Institutions: Philadelphia College of Osteopathic Medicine, National Board of Medical Examiners, Pennsylvania State University, Penn State Milton S. Hershey Medical Center, Medical College of Wisconsin, Mayo Clinic, Mayo Clinic in Florida, Wake Forest University Health Sciences, Wake Forest University, Johns Hopkins University, Johns Hopkins Medicine, University of Pennsylvania, University of Michigan, Lahey Hospital and Medical Center, University of Minnesota, University of Washington
Language: English
Subfield: Clinical Neurology
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
Funder: Cytokinetics
OpenAlex ID: W2884658318