Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells
Year: 2017
Type: article
Abstract: (Cell Reports 15, 1024–1036; May 3, 2016) In the originally published version of this article, the concentration of dual-SMAD inhibitors used was incorrectly reported in the Supplemental Experimental Procedures as “0.1 mM LDN193189 (Stemgent) and 10 mM SB431542 (Tocris)” instead of “0.1 μM LDN193189 (Stemgent) and 10 μM SB431542 (Tocris).” The Supplemental Experimental Procedures section has now been corrected online. The authors regret this error. Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor CellsTopol et al.Cell ReportsApril 21, 2016In BriefTopol et al. examine the role of decreased miR-9 levels in a subset of schizophrenia patient-derived neural progenitor cells from two independent cohorts. They observe a strong correlation between miR-9 expression and miR-9 regulatory activity. Manipulation of miR-9 impacts neural migration most likely through changes to many indirect miR-9 targets. Full-Text PDF Open Access
Source: Cell Reports
Authors: Aaron Topol, Shijia Zhu, Brigham J. Hartley, Jane English, Mads E. Hauberg, Ngoc Tran, Chelsea Ann Rittenhouse, Anthony Simone, Douglas M. Ruderfer, Jessica Johnson, Ben Readhead, Yoav Hadas, Peter A. Gochman, Ying-Chih Wang, Hardik Shah, Gerard Cagney, Judith Rapoport, Fred H. Gage, Joel T. Dudley, Pamela Sklar, Manuel Mattheisen, David Cotter, Gang Fang, Kristen J. Brennand
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $5,620
Award: G1370493877
OpenAlex ID: W2903579145